Rheumatoid Arthritis - A Guide To The Clinical And...
Rheumatoid Arthritis - A Guide to the Clinical and Laboratory Aspects (9871-10)
Explore the clinical findings and criteria for diagnosis including the pathogenesis and pathology of rheumatoid arthritis. The course outlines the hematological features of the disease and discusses the use of laboratory tests for the detection of inflammation in a patient. The concept of an antibody to human IgG seen with rheumatoid factor and the diagnostic value of many rheumatoid arthritis-associated antibodies will be studied.
PEP hours: 16
CPS credits: 1.0
Course Type: Express
Start Date: Upon registration
Completion: Up to 52 weeks
Delivery: PDF via email
Equipment: Computer with Internet is required
- Describe the incidence and clinical findings of a patient with rheumatoid arthritis (RA).
- List the criteria for diagnosis recommended by the American Rheumatism Society.
- Describe the concept of inflammation in RA patients as a cardiac risk factor.
- Describe briefly the pathogenesis and pathology of rheumatoid arthritis.
- Outline the hematological features of rheumatoid arthritis in terms of defective iron metabolism and anemia of chronic disease.
- Describe the role of genetics in RA.
- Discuss the use of tests for detecting the presence of inflammation in a patient. These tests would include the ESR and CRP in more detail, and the value for measurement of acute phase reactant proteins.
- Describe the normal findings seen in the laboratory evaluation of joint fluid.
- List the changes anticipated in the joint fluid from a RA patient.
- Outline the role of rheumatoid factor in the etiology of RA.
- Describe the concept of an antibody to human IgG as seen with rheumatoid factor.
- Explain how the presence of RF in a serum will affect certain tests in the laboratory.
- Discuss the interpretation of the rheumatoid factor test in terms of its PPV and PNV.
- List and include the relative diagnostic value of the many rheumatoid arthritis-associated antibodies.
- Explain the role of cytokines in the RA disease process.
- Discuss the importance of making a rapid and accurate diagnosis in those patients that present with symptoms consistent with early rheumatoid arthritis.
- Explain the logic used in establishing the appropriate treatment protocols for patients with rheumatoid arthritis.
- Describe the differences between the two classes of drugs termed NSAIDS and DMARDS.
- Review the newer treatment options using recombinant technology.
- Calculate test sensitivity, specificity, PPV and PNV when data is provided from laboratory or clinical trials.
Author/Instructor: John Chapman, FCSMLS, FIMLS, CLSp(H)
Version Date: July 2008