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Proteins, Antibodies And Immunoglobulins

 Proteins, Antibodies and Immunoglobulins (9806-09) Describe the nature of proteins from the basic molecular structure of amino acids through to the complex macro molecules that make up the body's humoral immune system. Review in detail each of the individual immunoglobulins from the molecular structure to the individual biological properties. Finally, a short review of the immunoglobulin levels seen in both health and disease states will be given. Version Date: December 2009

Code 9806-09
Level Advanced

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Additional Details

PEP hours: 11
CPS credits: 0.7
Level: Advanced
Course Type: Express

Start Date: Upon registration
Completion: Up to 52 weeks
Delivery: PDF via email

Prerequisites: None
Textbook: N/A
Equipment: Computer with Internet is required

Learning Outcomes:

  • Briefly describe the structure of proteins.
  • List the hemoglobins which show significant abnormalities in function due to a single amino acid alteration.
  • List the names and symbols for each of the 20 amino acids.
  • Draw the basic four chain structure of a simple immunoglobulin molecule.
  • Draw each individual immunoglobulin molecule and label each of the significant features in detail.
  • Describe briefly the methods for density gradient ultracentrifugation and gel filtration chromatography.
  • Outline the specific changes that result in the allotypic changes seen in both Light and Heavy chains of immunoglobulins.
  • Outline the specific features unique to the immunoglobulin molecule.
  • List the biological properties of each immunoglobulin type.
  • Complete a table to summarize the individual properties of each of the immunoglobulins.
  • Describe the significance of immunoglobulin sub-classes.
  • Outline the specific features of secretory immunoglobulins.
  • Describe the properties unique to the primary immune response.
  • Outline briefly the relationship of IgD and IgM to B cell maturation.
  • Describe the nature of the allergic response and the role of IgE.
  • Tabulate some of the clinical states that have increases in one or more immunoglobulins.

Author/Instructor: John Chapman, FCSMLS, FIMLS, CLSp(H)
Version Date: December 2009