Non-Malignant Disorders Of Leukocytes
Non-Malignant Disorders Of Leukocytes (9826-08)
Review neutrophils and other leukocytes to sharpen your skills as you differentiate qualitative, functional and morphological changes due to drugs, congenital disorders and other conditions.
PEP hours: 15
CPS/ART credits: 0.6
- Give the normal ranges for neutrophils and other granulocytes.
- Define the terms neutrophilia and neutropenia.
- Outline the body’s regulation of granulopoiesis
- List the causes of neutropenia into the major groups of under production and increased destruction.
- Describe the nature of the cytoplasmic granules of neutrophils and eosinophils
- Present in more detail the causes of neutrophil under production.
- List the common drugs which have an effect on neutrophil numbers.
- Tabulate the approach to investigating a child with neutropenia.
- Tabulate the congenital disorders of neutropenia.
- List the conditions in which neutropenia are a secondary phenomenon.
- Describe the major causes for neutrophilia.
- Define the term leukemoid reaction and how it may be differentiated from leukemia.
- Describe the qualitative abnormalities of neutrophils.
- Tabulate the functional abnormalities of neutrophil dysfunction.
- Describe the morphological abnormalities seen in the inherited disorders of neutrophils.
- Outline the composition of the specific granules of eosinophils.
- List the genetic abnormalities seen in: Cyclic neutropenia, Kostmann’s syndrome, Chediak Higashi syndrome and Wiscott-Aldrich syndrome.
- Describe the defect in the most common form of Severe Combined Immune Deficiency.
- Describe the role of eosinophils in the body’s response to parasitic infection.
- Explain the different origins of the basophil and the mast cell.
- Describe the role of mast cells in the body.
- Tabulate the benign disorders of lymphocytes
- List the conditions associated with lymphopenia
- Tabulate the immunoglobulin levels seen in the various immunodeficiency states.
Instructor: John Chapman, FCSMLS, FIMLS, CLSp(H)
Equipment: Computer with Internet is required
Start Date: Upon registration
Completion: Up to 52 weeks
Version Date: February 2008