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Monoclonal Antibodies: Theory And Production

 Monoclonal Antibodies: Theory and Production (9848-10) Review the topic of monoclonal antibodies and the differences between polyclonal and monoclonal antibodies. By the end of this module the student should have a good understanding of the fundamentals of monoclonal antibodies in laboratory medicine and as their potential of treating a wide range of serious diseases. Version Date: September 2010

Code 9848-10
Level Advanced

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Additional Details

PEP hours: 14
CPS credits: 0.6
Level: Advanced
Course Type: Express
Start Date: Upon registration
Completion: Up to 52 weeks
Delivery: PDF via email
Prerequisites: None
Textbook: N/A
Equipment: Computer with Internet is required
Learning Outcomes:
  • Review the nature of antigens, antibodies and immunogenicity
  • Describe the structure and nature of antibodies
  • Draw the relevant parts of a plasma cell
  • Describe the principles of cell fusion and hybridoma production.
  • Outline the method of monoclonal antibody production.
  • Tabulate the advantages and disadvantages of monoclonal antibodies.
  • Describe briefly the principles behind chimeric and humanized monoclonal antibodies
  • Outline how monoclonal antibodies are purified
  • Describe the terminology for naming monoclonal antibodies as set out by USANC
  • Describe the role transgenic mice play in monoclonal antibody preparation
  • Explain the principles of antigen
Author/Instructor: John Chapman, FCSMLS, FIMLS, CLSp(H)
Version Date: September 2010