• Course Catalogue
• Educational Offerings
  • Course Catalogue
  • Exam Catalogue
  • LABCON2012 Virtual Pass
  • Certificate Programs
• Authors and Instructors
• F.A.Q.
  • Navigating the Course Catalogue
  • How do I register in a course?
  • How do I register in an exam?
  • When and how will I be able to access my course?
  • What is an invigilator?
  • When and how will I get my course results?
• Learning Resources
  • Online Bookstore
  • Course Assessments
  • Loan Library
  • Acknowledging Sources
• Professional Recognition Programs
  • Professional Enhancement Program
  • Certificate of Continuing Professional Studies
• Leadership Programs
• Degree Completion Programs
• Academic Dishonesty
  • Academic Dishonesty Policy
  • Academic Integrity Resources
• e-Learning Society

Macrocytic Anemias

Additional Details

PEP hours: 9
CPS/ART credits: 0
Level: Basic
Course Type: Express

Start Date: Upon registration
Completion: Up to 52 weeks
Delivery: PDF via email

Prerequisites: None
Textbook: N/A
Equipment: Computer with Internet is required

Learning Outcomes:

• Classify the macrocytic anemias into two major groups
• Write a definition for megaloblastic anemia
• Briefly describe the metabolism and functions of vitamin B12 and folic acid
• State the underlying cause of all types of megaloblastic anemias
• Describe the specific causes (3) of the anemia in megaloblastic anemias
• Name the two major types of megaloblastic anemia
• List and discuss typical laboratory findings in a megaloblastic anemia
• Differentiate (morphologically) a megaloblast from a normoblast (erythroblast)
• Name the cell stages of the megaloblastic erythroid series
• List several causes of vitamin B12 deficiency
• Write a definition of pernicious anemia and discuss its specific etiology including the production and role of intrinsic factor and the types of autoantibodies
• List several lab tests to identify: vitamin B12 deficiency anemia; abnormal vitamin B12 absorption; pernicious anemia
• Briefly define folic acid deficiency anemia, including its major causes, and list the most important laboratory test for its diagnosis
• Briefly describe some disorders that show bone marrow megaloblasts but which fail to respond to therapy with vitamin B12 or folate
• List the three major categories of non-megaloblastic macrocytic anemias and some specific causes
• List lab findings which differentiate non-megaloblastic anemias from megaloblastic anemias

Author/Instructor: Bill McTaggart, BSc, ART
Version Date: April 2010