Explore the biochemistry and measurement of lipids and how they interact within the body. Lipids are a vital part of homeostasis but, like so many other aspects of body chemistry, have a potential of negative implications when things go wrong. In addition to genetic aberrations, inappropriate lifestyle activities may impart profound clinical effects.
PEP hours: 11
CPS/ART credits: 0.6
- Give the definition of a lipid and name five classes.
- Discuss fats and lipids in terms of a source of the body’s energy supply.
- Describe the digestion and absorption of dietary lipids.
- Give the definition of a glyceride (acylglycerol) and describe the synthesis of the three types of glycerides.
- State the importance of triglycerides and discuss their metabolism.
- Give the definition of a fatty acid. State the importance of chain length, and double bonds on the nomenclature and properties of a fatty acid.
- Define the natures of essential fatty acids.
- Name the essential fatty acids.
- Describe the properties of fatty acids.
- Discuss the physiology of fatty acids
- Name and describe the formation of ketone bodies.
- Give the definition of a steroid, write its name and formula, name important steroids and state the characteristics that differentiate steroids.
- Identify the structures of important steroids.
- Write the structure of cholesterol; describe its chemistry, functions and excretion. Name the bile acids and state their functions.
- Name the lipoproteins and describe their characteristics and nomenclature.
- Discuss the relationship between LDL, HDL and coronary heart disease.
- Describe apolipoprotein A-1 and B and their importance in coronary heart disease.
- Describe the estimation of triglycerides.
- Describe the estimation of cholesterol (total, free and esterified).
- Describe the estimation of HDL-cholesterol and of LDL-cholesterol.
- List the risk factors for coronary heart disease
- State the biochemistry of apolipoprotein A-1 and B (B-48 and B-100)
- Describe the six phenotypes of hyperlipoproteinemia.
- Discuss the synthesis of lecithin (L) and sphingomyelin (S) at various periods of gestation
Instructor: John Chapman, FCSMLS, FIMLS, CLSp(H)
Equipment: Computer with Internet is required
Start Date: Upon registration
Completion: Up to 52 weeks
Version Date: February 2009