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Introduction To Platelet Structure And Function

 Introduction To Platelet Structure And Function (9817-10) Learn about platelet production, kinetics and regulation, aggregation and understand the effect of drugs on platelets. Platelet factors and the arachidonic acid-prostacyclin pathways are also discussed. Version Date: January 2010

Code 9817-10
Level Advanced

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Additional Details

PEP hours: 11
CPS credits: 0.7
Level: Advanced
Course Type: Express

Start Date: Upon registration
Completion: Up to 52 weeks
Delivery: PDF via email

Prerequisites: None
Textbook: N/A
Equipment: Computer with Internet is required

Learning Outcomes:

  • Describe the production of platelets in the body including platelet kinetics, life span and regulation.
  • Describe in detail, and draw the ultrastructure of a typical platelet.
  • Outline the relationships between the different structural zones of the platelet.
  • Describe the current understanding of the regulatory protein thrombopoietin.
  • Briefly describe the formation of a platelet hemostatic plug.
  • Give a detailed review of the platelet interaction with the vessel wall.
  • Describe the process of aggregation and list the agents that initiate it.
  • List many of the substances available over the counter that contains aspirin.
  • Outline the logic for daily aspirin therapy.
  • Describe the agents that inhibit platelet aggregation.
  • Prepare a list of drugs that have an effect on platelet function
  • Outline the specific features of PF3 and PF4.
  • Describe schematically the arachidonic acid - prostacyclin pathways.
  • List the compounds released from platelets upon activation.
  • Describe the effect of ethanol on platelets.

Author/Instructor: John Chapman, FCSMLS, FIMLS, CLSp(H)
Version Date: January 2010