Genetics For Blood Bankers
Genetics for Blood Bankers (9840-10)
Explore the basic science of molecular biotechnology with emphasis on the applications in transfusion science.
PEP hours: 14
CPS/ART credits: 1.0
- Define the terms used for the classical genetics listed in Appendix A
- Recognize patterns of inheritance with reference to blood group systems.
- Understand the mechanism of the central dogma of protein synthesis.
- Relate the structural and functional proteins to the synthesis of various blood group antigens.
- Understand the process of protein synthesis
- Define exon, intron, mRNA splicing, missense and nonsense mutation.
- Give examples of blood group polymorphism due to mutation.
- Calculate gene frequencies given blood group antigen frequencies in a defined population.
- Calculate number of donor units should be screened for a patient with multiple alloantibodies.
- Understand the process of monoclonal antibody production
- Understand the rules of exclusion in paternity testing
- Understanding the basic principle of gene cloning and production of recombinant therapeutic plasma proteins
- Appreciate the knowledge of the genetic background of each blood group systems.
- Be aware of the therapeutic plasma proteins that can be produced by recombinant technology
Instructor: Eric Ching, ART, MT(ASCP)SBB
Equipment: Computer with Internet is required
Start Date: Upon registration
Completion: Up to 52 weeks
Version Date: November 2010