Language: Français


 Fibrinolysis (9841-08) Build upon your knowledge of the hemostasis system as you consider the fibrinolytic system. Learn how this system lyses unwanted clots and becomes involved with the process of healing. Examine how the fibrinolytic system depends on appropriate activation, production of peptides and action of enzymes in order to function. Disseminated intravascular coagulation (DIC) is discussed in terms of common "trigger" mechanisms and laboratory findings, as well as the use of agents in therapeutic fibrinolysis. Version Date: November 2008

Code 9841-08
Level Advanced

Member Price


Non-Member Price



Additional Details

PEP hours: 16
CPS credits: 1.0
Level: Advanced
Course Type: Express
Start Date: Upon registration
Completion: Up to 52 weeks
Delivery: PDF via email
Prerequisites: None
Textbook: N/A
Equipment: Computer with Internet is required
Learning Outcomes:
  • Describe the role of fibrinolysis in hemostasis
  • List the components, with their properties, functionally involved with fibrinolysis
  • Briefly describe the role of fibrinolysis and the metalloprotein matrix
  • Describe the properties of plasminogen activators
  • Explain the function of plasmin and its production from plasminogen
  • Tabulate the properties of plasminogen inhibitors
  • Outline the features of hyperfibrinolytic states
  • Describe the clinical entity of DIC and its common trigger mechanisms
  • Discuss the laboratory findings of DIC
  • Describe the role of antithrombin III both as an inhibitor and its role with heparin therapy
  • Describe how fibrinogen is affected by thrombin and broken down by plasmin to form FDP
  • Outline the use of agents used in therapeutic fibrinolysis
Author/Instructor: John Chapman, FCSMLS, FIMLS, CLSp(H)
Version Date: November 2008