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Enzymology - Part II

 Enzymology - Part II (9838-08) Learn how and when specific enzymes are measured and improve your ability to relate enzyme levels to disease. Continue your studies from Enzymology - Part I as you consider enzymes of clinical importance. You will consider detailed enzyme profiles, their tissues of origin and factors that affect their specific activity.

Code 9838-08
Level Basic

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Additional Details

PEP hours: 11
CPS credits: 0
Level: Basic
Course Type: Express
Start Date: Upon registration
Completion: Up to 52 weeks
Delivery: PDF via email
Prerequisites: Enzymology - Part I (9837-08)
Textbook: N/A
Equipment: Computer with Internet is required
Learning Outcomes:
  • Explain the basis for the measurement of enzymes
  • Define plasma specific enzymes, non-plasma specific enzymes, enzymes of secretion, enzymes of cellular metabolism
  • Name the enzymes of importance in the diagnosis of alcoholic cirrhosis, bone disease, hepatobiliary disease, hepatocellular disease, muscle conditions, myocardial infarction, and pancreatic disease.
  • Define the specimen collection and storage conditions for each enzyme.
  • State the effect of hemolysis, storage temperature and storage pH on measured enzyme activity.
  • For the various enzymes, state/define/explain, as appropriate, their IUB name, EC number, classification, optimum pH, origin, mechanism of action, substrates usable, inhibitors, cofactors, specimen characteristics, assay principle, compound actually measured in the final step, precautions necessary, reference range and clinical significance.
  • Name the enzymes which are useful in the diagnosis of myocardial infarction.
  • Name specific enzymes which are useful in the diagnosis of hepatobiliary and hepatocellular conditions.
Author/Instructor: John Chapman, FCSMLS, FIMLS, CLSp(H)
Version Date: December 2008