Cytokines - The Interleukins
Cytokines - The Interleukins (9853-10)
Review the general nature of cytokines and in particular, one class of cytokine - the interleukins. The interleukins show multiple effects. They may act individually expressing a single function or more likely initiate a series of multiple functions.
PEP hours: 25
CPS credits: 1.7
Course Type: Express
Start Date: Upon registration
Completion: Up to 52 weeks
Delivery: PDF via email
Equipment: Computer with Internet is required
- Define the following terms: cytokine, chemokine, lymphokine and monokine.
- Compare the actions of cytokines in comparison to the functions of hormones.
- Describe the three types of chemical signaling in the body
- Describe the clinical condition known as cytokine storm.
- List the causes of cytokine storm
- Discuss the classification system that depends on the three dimensional structure of cytokine receptors.
- Describe the general features of the interleukins.
- Describe the features that make IL1 considered the prototypic interleukin.
- List the interleukins that may be of use therapeutically.
- Describe the interleukins that act as specific growth factors for eosinophils and neutrophils.
- Describe the interleukin that is a major autocrine growth modulator for myeloma and associated with plasma cell leukemia.
- Discuss the use of interleukins as growth factors and their potential use for repopulation of bone marrow following chemotherapy and bone marrow transplant.
Author/Instructor: John Chapman, FCSMLS, FIMLS, CLSp(H)
Version Date: November 2010