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Case Studies: Patients With Platelet Disorders - Series One

 Case Studies: Patients with Platelet Disorders - Series One (9863-14) Learn how to assess information from the problem, clinical data and laboratory findings to resolve disorders such as neonatal alloimmune thrombocytopenia, Gray platelet syndrome, Glanzmann's thrombasthenia, post-infectious thrombocytopenia, and the use and abuse of bleeding times. Version Date: March 2014

Code 9863-14
Level Advanced

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Additional Details

PEP hours: TBD
CPS credits: TBD
Level: Basic
Course Type: Express

Start Date: Upon registration
Completion: Up to 52 weeks
Delivery: PDF via email

Prerequisites: None
Textbook: N/A
Equipment: Computer with Internet is required

Learning Outcomes:

  • Describe the mechanisms of neonatal alloimmune thrombocytopenia
  • Detail the difference between alloimmune thrombocytopenic purpura and HDNB
  • Tabulate the characteristics of common platelet antigens
  • Discuss the value of testing for platelet antigens
  • Outline the features of platelets with defects of platelet granules
  • Describe the morphological appearance of platelets with Gray platelet syndrome
  • Describe the appearance of platelets with abnormal platelet morphology
  • Discuss the diagnostic and treatment options for patients with Gray platelet syndrome
  • Describe the functional defects seen in patients with deficiencies of specific platelet glycoproteins
  • Briefly review the genetics of patients with platelet functional disorders
  • Explain the theory of platelet aggregation tests
  • Tabulate the clinical and laboratory results seen in patients with hereditary platelet functional disorders
  • Discuss the logic and value of using the terms “idiopathic” and “immune” thrombocytopenia
  • Outline the laboratory features of childhood thrombocytopenia
  • Discuss in detail the pros and cons of the bleeding time test
  • List the many causes for an abnormal bleeding time test
  • Tabulate some of the many drugs that interfere with platelet function tests
  • Describe the procedure for performing a clinically significant bleeding time test
  • Prepare sensitivity, specificity, positive predictive value and negative predictive value results from laboratory data provided

Author/Instructor: John Chapman, FCSMLS, FIMLS, CLSp(H)
Version Date: March 2014