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Case Studies: Patients With Platelet Disorders - Series Two

 Case Studies: Patients with Platelet Disorders - Series Two (9864-08) Continue to increase your knowledge and problem solving skills by using five case studies to analyse HELLP syndrome, idiopathic thrombocytopenia purpura, thrombotic thrombocytopenic purpura, Von Willebrand's disease, and the hyper-responder to aspirin.

Code 9864-08
Level Basic

Member Price

$0

Non-Member Price

$110

 

Additional Details

PEP hours: 16
CPS/ART credits: 0
Level: Basic
Course Type: Express
 
Start Date: Upon registration
Completion: Up to 52 weeks
Delivery: PDF via email
 
Prerequisites: Case Studies: Patients with Platelet Disorders - Series One (9863-08)
Textbook: N/A
Equipment: Computer with Internet is required
 
Learning Outcomes:
  • Discuss the laboratory options in the investigation of a patient that presents with a laboratory picture of microangiopathy.
  • Outline the specific laboratory findings of the HELLP Syndrome.
  • Tabulate the laboratory findings seen in thrombocytopenic disorders.
  • Define the HELLP Syndrome and how it is differentiated from other similar syndromes (DIC,AFLP,TTP,HUS,ITP)
  • Discuss the differences and similarities between childhood and adult immune thrombocytopenia.
  • Discuss the value of testing patients for platelet antibodies.
  • Review the treatment options for patients with ITP and how the laboratory status assists in making these decisions.
  • Tabulate the various forms of drug therapies and their respective response rates in patients with ITP.
  • Describe the clinical and laboratory findings seen in TTP.
  • Discuss the role of vWF in the etiology of TTP.
  • Review briefly the history of TTP and how it relates to today’s understanding of the pathophysiology.
  • Outline the laboratory differences between TTP, HUS and DIC.
  • Outline the specific role of vWF and ADAMTS-13 in TTP.
  • Review the clinical and laboratory findings of type 1 vWD.
  • Discuss the laboratory tests (coagulation, platelet function, aggregation) and their role in diagnosing vWD.
  • Define the various factors involved in vWD: factor VIII, factor VIIIC, factor VIII:Ag, factor VIIIRcof, factor VIII:vWF complex and vWF.
  • Tabulate the laboratory features of type 1, type 2a, type 2b and type 2c vWD.
  • List the overall diagnostic features (clinical and laboratory) of the various vWD types.
  • Discuss the treatment options for the most common vWD types.
  • Outline the role of aspirin in defective platelet function and the identification of hyper responders.
  • Briefly outline the sequence of events that take place when platelets are activated.
  • Draw conceptually the arachidonic acid, cyclo-oxygenase and lipogenase pathways.
  • List the manner by which the biochemical compounds formed influence platelet function.
Author/Instructor: John Chapman, FCSMLS, FIMLS, CLSp(H)
Version Date: December 2008